Biomolecular Systems and Design Lab
We investigate how peptides self-assemble and interact with interfaces to control biological function and dysfunction. Using biophysical experiments and molecular simulations, we uncover mechanisms of peptide aggregation and membrane activity that link disease-related processes with the rational design of biomolecular materials.
Join the Lab
The Biomolecular Systems and Design Lab welcomes motivated students with backgrounds in chemistry, biochemistry, biophysics, or related disciplines. Projects typically combine experimental and computational approaches, but applicants are not expected to have prior experience in all methods. Information on open positions can be found via the Contact page. Prospective students are also welcome to get in touch to discuss potential opportunities.
Research Areas
We study how peptides self-assemble into ordered structures, including amyloid fibrils. Our work focuses on how sequence, environment, and interfaces regulate aggregation pathways relevant to age-related and neurodegenerative diseases.
Interfaces such as membranes and nanoparticles strongly modulate biomolecular behavior. We investigate peptide-interface interactions and their role in membrane activity, transport, and biological function or dysfunction.
Using mechanistic insights, we engineer functional biomolecular assemblies. Our work aims at the rational design of peptide-based and hybrid materials with controlled structure and biological activity.
